Electrochemical aptasensor for lung cancer-related protein detection in crude blood plasma samples

Zamay, G. S.; Zamay, T. N.; Kolovskii, V. A.; Shabanov, A. V.; Glazirin, Yu. E.; Veprintsev, D. V.; Krat, A. V.; Zamay, S. S.; Kolovskaya, O. S.; Gargaun, A. E.; Sokolov, A. A.; Modestov, A. A.; Artyukhov, I. P.; Chesnokov, N. V.; Petrova, M. M.; Berezovski, M. V.; Zamay, A. S.

doi:10.1038/srep34350

Автор:

Zamay, G. S.

Zamay, T. N.

Kolovskii, V. A.

Shabanov, A. V.

Glazirin, Yu. E.

Veprintsev, D. V.

Krat, A. V.

Zamay, S. S.

Kolovskaya, O. S.

Gargaun, A. E.

Sokolov, A. A.

Modestov, A. A.

Artyukhov, I. P.

Chesnokov, N. V.

Petrova, M. M.

Berezovski, M. V.

Zamay, A. S.

Коллективный автор:

Институт фундаментальной биологии и биотехнологии

Кафедра медицинской биологии

Дата:

2016-09

Журнал:

Scientific Reports

Квартиль журнала в Scopus:

Квартиль журнала в Web of Science:

Библиографическое описание:

Zamay, G. S. Electrochemical aptasensor for lung cancer-related protein detection in crude blood plasma samples [Текст] / G. S. Zamay, T. N. Zamay, V. A. Kolovskii, A. V. Shabanov, Yu. E. Glazirin, D. V. Veprintsev, A. V. Krat, S. S. Zamay, O. S. Kolovskaya, A. E. Gargaun, A. A. Sokolov, A. A. Modestov, I. P. Artyukhov, N. V. Chesnokov, M. M. Petrova, M. V. Berezovski, A. S. Zamay // Scientific Reports. — 2016. — . — .

Аннотация:

The development of an aptamer-based electrochemical sensor for lung cancer detection is presented in the work.A highly specific DNA-aptamer, LC-18, selected to postoperative lung cancer tissues was immobilized onto a gold microelectrode and electrochemical measurements were performed in a solution contaning the redox marker ferrocyanide/ferricyanide. As a result, the electrochemical aptasensor was able to detect cancer-related targets in crude blood plasma of lung cancer patients.

Коллекции:

Статьи в научных журналах (эффективный контракт) [5211]

Метаданные:

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