Applications of luminous bacteria enzymes in toxicology
URI (for links/citations):http://elib.sfu-kras.ru/handle/2311/27950
Kratasyuk, V. A.
Esimbekova, E. N.
Институт фундаментальной биологии и биотехнологии
Journal Name:Combinatorial Chemistry and High Throughput Screening
Journal Quartile in Scopus:Q2
Journal Quartile in Web of Science:Q3
Bibliographic Citation:Kratasyuk, V. A. Applications of luminous bacteria enzymes in toxicology [Текст] / V. A. Kratasyuk, E. N. Esimbekova // Combinatorial Chemistry and High Throughput Screening. — 2015. — Т. 18 (№ 10). — С. 952-959
This review describes the principle and applications of bioluminescent enzymatic toxicity bioassays. This type of assays uses bacterial coupled enzyme systems: NADH:FMN-oxidoreductase and luciferase to replace living organisms in developing cost-competitive biosensors for environmental, medical and industrial applications. These biosensors instantly signal chemical and biological hazards and allow for detecting a great amount of toxic compounds with advantages associated with fast results, high sensitivity, simplicity, low cost and safety of the procedure.