Applications of luminous bacteria enzymes in toxicology
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URI (для ссылок/цитирований):
https://elib.sfu-kras.ru/handle/2311/27950Автор:
Kratasyuk, V. A.
Esimbekova, E. N.
Коллективный автор:
Институт фундаментальной биологии и биотехнологии
Кафедра биофизики
Дата:
2015-12Журнал:
Combinatorial Chemistry and High Throughput ScreeningКвартиль журнала в Scopus:
Q2Квартиль журнала в Web of Science:
Q3Библиографическое описание:
Kratasyuk, V. A. Applications of luminous bacteria enzymes in toxicology [Текст] / V. A. Kratasyuk, E. N. Esimbekova // Combinatorial Chemistry and High Throughput Screening. — 2015. — Т. 18 (№ 10). — С. 952-959Аннотация:
This review describes the principle and applications of bioluminescent enzymatic toxicity bioassays. This type of assays uses bacterial coupled enzyme systems: NADH:FMN-oxidoreductase and luciferase to replace living organisms in developing cost-competitive biosensors for environmental, medical and industrial applications. These biosensors instantly signal chemical and
biological hazards and allow for detecting a great amount of toxic compounds with advantages associated with fast results, high sensitivity, simplicity, low cost and safety of the procedure.