Оптимизация процесса получения биологически активного диацетата бетулина из исходной и активированной бересты березы

Abstract

It was studied the influence of acetylation process conditions of initial and activated birch bark on the yield and composition of the products. The structure of biologically active betulin diacetate was confirmed by physicochemical methods. Optimal modes of betulin diacetate obtaining were established by experimental and computational methods. Optimal regimes of the original one-step process for the preparation of betulin diacetate from initial and activated birch bark were established by experimental and computational methods