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Bio-functionalization of phytogenic Ag and ZnO nanobactericides onto cellulose films for bactericidal activity against multiple drug resistant pathogens
Автор | Baker, S. | |
Автор | Прудникова, С. В. | |
Автор | Шумилова, А. А. | |
Автор | Перьянова О. В | |
Автор | Жарков, С. М. | |
Автор | Кузьмин, А. П. | |
Дата внесения | 2020-01-20T07:58:03Z | |
Дата, когда ресурс стал доступен | 2020-01-20T07:58:03Z | |
Дата публикации | 2019-04 | |
Библиографическое описание | Baker, S. Bio-functionalization of phytogenic Ag and ZnO nanobactericides onto cellulose films for bactericidal activity against multiple drug resistant pathogens [Текст] / S. Baker, С. В. Прудникова, А. А. Шумилова, Перьянова О. В, С. М. Жарков, А. П. Кузьмин // Journal of Microbiological Methods. — 2019. — Т. 159. — С. 42-50 | |
ISSN | 01677012 | |
URI (для ссылок/цитирований) | https://www.sciencedirect.com/science/article/pii/S0167701218310327?via%3Dihub | |
URI (для ссылок/цитирований) | https://elib.sfu-kras.ru/handle/2311/129407 | |
Аннотация | The present study describes the synthesis of silver and zinc oxide nanobactericides from the phytogenic source Bupleurum aureum. The synthesized nanobactericides were characterized and evaluated for bio-functionalization onto bacterial cellulose membrane which was synthesized by Komagataeibacterxylinus B-12068 culture strain. The synthesis of nanobacterides were initially confirmed using UV–Visible spectroscopy which indicated localized surface resonance (LSPR) peaks at 415 nm for silver nanobactericides and 280 nm for zinc nanobactericides. The nature of the capping agent for synthesized nanobactericides was predicted using FTIR which confirmed the presence of functional moieties. XRD analysis revealed their crystalline nature while morphological characteristics were studied using TEM which confirmed the polydispersity of nanobactericides with the average size in the range of 20–25 nm. The nanobactericides were tested for their antimicrobial activity against seven multi-drug resistant pathogens which were clinically isolated from patients suffering from a myriad of microbial infections. The tested pathogens had antimicrobial resistance to ten different antibiotics and have been reported to be the major cause of nosocomial infections. The nanobactericides displayed significant activity against the test pathogens. Silver nanobactericides showed the highest activity against Escherichia coli strain 55 with a 24 mm zone of inhibition while zinc oxide nanobactericides displayed the highest activity against methicillin-resistant Staphylococcus aureus (MRSA) with a 20 mm inhibition zone. The bio- functionalized cellulose films (BCF) were characterized using SEM along with physicochemical analysis. The BCF's were evaluated for antibacterial activity against test pathogens which resulted in marked antimicrobial potential against multi-drug resistant bacteria and therefore has the potential to be utilized as an efficient alternative to counter drug resistant pathogens. © 2019 Elsevier B.V. | |
Тема | Bacterial cellulose | |
Тема | Bio-functionalization | |
Тема | Bupleurum aureum | |
Тема | Multi-drug resistance pathogens | |
Тема | Silver nanobactericides | |
Тема | Zinc oxide nanobactericides | |
Название | Bio-functionalization of phytogenic Ag and ZnO nanobactericides onto cellulose films for bactericidal activity against multiple drug resistant pathogens | |
Тип | Journal Article | |
Тип | Journal Article Preprint | |
Страницы | 42-50 | |
ГРНТИ | 34.27 | |
Дата обновления | 2020-01-20T07:58:03Z | |
DOI | 10.1016/j.mimet.2019.02.009 | |
Институт | Институт нефти и газа | |
Институт | Политехнический институт | |
Подразделение | Базовая кафедра химии и технологии природных энергоносителей и углеродных материалов | |
Подразделение | Кафедра материаловедения и технологии обработки материалов | |
Журнал | Journal of Microbiological Methods | |
Квартиль журнала в Scopus | Q3 | |
Квартиль журнала в Web of Science | Q3 |