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Structural variants in 3000 rice genomes
Автор | Roven, Rommel Fuentes | |
Автор | Dmytro, Chebotarov | |
Автор | Jorge, Duitama | |
Автор | Sean, Smith | |
Автор | Juan Fernando De, La Hoz | |
Автор | Marghoob, Mohiyuddin | |
Автор | Rod A. Wing | |
Автор | Kenneth L. McNally | |
Автор | Tatiana, Tatarinova | |
Автор | Andrey, Grigoriev | |
Автор | Ramil, Mauleon | |
Автор | Nickolai, Alexandrov | |
Дата внесения | 2020-01-20T07:16:01Z | |
Дата, когда ресурс стал доступен | 2020-01-20T07:16:01Z | |
Дата публикации | 2019-05 | |
Библиографическое описание | Roven, Rommel Fuentes. Structural variants in 3000 rice genomes [Текст] / Rommel Fuentes Roven, Chebotarov Dmytro, Duitama Jorge, Smith Sean, La Hoz Juan Fernando De, Mohiyuddin Marghoob, Rod A. Wing, Kenneth L. McNally, Tatarinova Tatiana, Grigoriev Andrey, Mauleon Ramil, Alexandrov Nickolai // Genome Research. — 2019. — Т. 29 (№ 5). — С. 870-880 | |
ISSN | 10889051 | |
URI (для ссылок/цитирований) | http://www.genome.org/cgi/doi/10.1101/gr.241240.118 | |
URI (для ссылок/цитирований) | https://elib.sfu-kras.ru/handle/2311/128822 | |
Аннотация | Investigation of large structural variants (SVs) is a challenging yet important task in understanding trait differences in highly repetitive genomes. Combining different bioinformatic approaches for SV detection, we analyzed whole-genome sequencing data from 3000 rice genomes and identified 63 million individual SV calls that grouped into 1.5 million allelic variants. We found enrichment of long SVs in promoters and an excess of shorter variants in 5′ UTRs. Across the rice genomes, we identified regions of high SV frequency enriched in stress response genes. We demonstrated how SVs may help in finding causative variants in genome-wide association analysis. These new insights into rice genome biology are valuable for understanding the effects SVs have on gene function, with the prospect of identifying novel agronomically important alleles that can be utilized to improve cultivated rice. | |
Тема | rice | |
Тема | genome | |
Тема | bioinformatis | |
Тема | agriculture | |
Название | Structural variants in 3000 rice genomes | |
Тип | Journal Article | |
Тип | Journal Article Preprint | |
Страницы | 870-880 | |
ГРНТИ | 34.23.57 | |
Дата обновления | 2020-01-20T07:16:01Z | |
DOI | 10.1101/gr.241240.118 | |
Институт | Институт фундаментальной биологии и биотехнологии | |
Подразделение | Базовая кафедра защиты и современных технологии мониторинга лесов | |
Журнал | Genome Research | |
Квартиль журнала в Scopus | Q1 | |
Квартиль журнала в Web of Science | Q1 |