Polyhydroxyalkanoates (PHA) for therapeutic applications
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URI (для ссылок/цитирований):
https://www.sciencedirect.com/science/article/pii/S0928493117333325?via%3Dihubhttps://elib.sfu-kras.ru/handle/2311/110946
Автор:
Junyu, Zhang
Шишацкая, Е. И.
Волова, Т. Г.
Da Silva, L. F.
Guo-Qiang, Chen
Коллективный автор:
Институт фундаментальной биологии и биотехнологии
Кафедра медицинской биологии
Дата:
2018-05Журнал:
Materials Science and Engineering CКвартиль журнала в Scopus:
Q1Квартиль журнала в Web of Science:
Q1Библиографическое описание:
Junyu, Zhang. Polyhydroxyalkanoates (PHA) for therapeutic applications [Текст] / Zhang Junyu, Е. И. Шишацкая, Т. Г. Волова, L. F. Da Silva, Chen Guo-Qiang // Materials Science and Engineering C. — 2018. — Т. 86. — С. 144-150Аннотация:
As intracellular carbon and energy storage materials, polyhydroxyalkanoates (PHA) are a diverse biopolyesters synthesized by many bacteria. PHA have been produced in large quantity for various application research including medical implants for approximately 30 years. Many studies demonstrated that PHA are promising implant materials due to their diverse and ascendant mechanical, biodegradable and tissue compatible properties. Importantly, common PHA biodegradation products including oligomers and monomers are also not toxic to the cells and tissues. Pharmaceutical applications of some PHA degradation products also have been reported. So far, no study has been reported to have any carcinogenesis result induced by any PHA or their biodegradation products. All results suggest that PHA could be developed into various bio-implant products.