Now showing items 1-10 of 48
Significance of the XRCC1 gene Arg399Gln polymorphism in the pathogenesis of the chronic myeloproliferative diseases
We investigated the association between Arg399Gln polymorphism in DNA repair gene XRCC1 and chronic myeloproliferative diseases. 79 patients with chronic myeloid leukemia (CML), 91 patient with polycythemia vera (PV), 132 ...
Selection of DNA Aptamers for Breast Cancer
A method of selection of DNA aptamers to breast tumor tissue based on the use of potoperative material has been developed. Breast cancer tissue were used as the positive target; the negative targets included benign tumor ...
Antitumor Effect of Arabinogalactan and Platinum Complex
The article presents the results of investigation of antitumor properties of platinum–arabinogalactan complex. We showed the ability of the complex to inhibit the growth of Ehrlich ascites tumor cells. It is found that the ...
Emerging aspects of nanotoxicology in health and disease: From agriculture and food sector to cancer therapeutics
Nanotechnology is an evolving scientific field that has allowed the manufacturing of materials with novel physicochemical and biological properties, offering a wide spectrum of potential applications. Properties of ...
The identifiability of patients with carcinogenic somatic mutation of Junus kinase-2 (V617FJAK2) within the framework of programs of dispensary and preventive examinations
The article presents results of identification of somatic mutation in in gene Junus kinase-2 (V617F JAK2) in blood samples of persons included in program of dispensarization of adult population and periodic preventive ...
Effect of Biomaterials of Medical Purpose on the Structural and Functional Features of Monocytes
The morphological and functional features of the monocytes in a short-term in vitro cultivation on substrates of biopolymer polyhydroxyalkanoate (PHA) in the presence of nanodiamonds (ND) and fullerene (F) were studied. ...