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Effect of Biomaterials of Medical Purpose on the Structural and Functional Features of Monocytes
Автор | Menzyanova, N. G. | |
Автор | Nikolaeva, E. D. | |
Автор | Vinokurova, D. V. | |
Автор | Shabanov, A. V. | |
Автор | Shershneva, A. M. | |
Автор | Shishatskaya, E. I. | |
Автор | Sukhova, K. V. | |
Дата внесения | 2017-06-16T10:22:26Z | |
Дата, когда ресурс стал доступен | 2017-06-16T10:22:26Z | |
Дата публикации | 2016-02 | |
Библиографическое описание | Menzyanova, N. G. Effect of Biomaterials of Medical Purpose on the Structural and Functional Features of Monocytes [Текст] / N. G. Menzyanova, E. D. Nikolaeva, D. V. Vinokurova, A. V. Shabanov, A. M. Shershneva, E. I. Shishatskaya, K. V. Sukhova // Journal of Siberian Federal University.: Biology. — 2016. — Т. 9 (№ 1). — С. 33-42 | |
URI (для ссылок/цитирований) | https://elib.sfu-kras.ru/handle/2311/32943 | |
Описание | Текст статьи не публикуется в открытом доступе в соответствии с политикой журнала. | |
Аннотация | The morphological and functional features of the monocytes in a short-term in vitro cultivation on substrates of biopolymer polyhydroxyalkanoate (PHA) in the presence of nanodiamonds (ND) and fullerene (F) were studied. It has been shown that ND and F in the studied concentrations did not affect the viability of monocytes in the short-term culture. The ratio of morphological classes in the presence of ND and F significantly different from the control group of cultivation. Effects of NA and F were characterized by dose-dependent. The formation of a protein corona on the surface of NA and F led to significant changes in the effects of nanoparticles and the formation of new quantitative relationships between morphological classes of monocytes in culture in vitro. The results allow to consider a short-term culture of monocytes in vitro as a model system for adequate assessment of the impact of new materials on the processes of differentiation of monocyte subpopulations. | |
Ссылка на другой сайт | http://journal.sfu-kras.ru/en/number/20176 | |
Тема | Biomaterials for medical uses | |
Тема | polyhydroxyalkanoates | |
Тема | monocytes | |
Тема | nanodiamonds | |
Тема | fullerenes | |
Название | Effect of Biomaterials of Medical Purpose on the Structural and Functional Features of Monocytes | |
Тип | Journal Article | |
Тип | Published Journal Article | |
Страницы | 33-42 | |
ГРНТИ | 34.57.21 | |
Дата обновления | 2017-06-16T10:22:26Z | |
DOI | 10.17516/1997-1389-2015-9-1-33-42 | |
Институт | Институт фундаментальной биологии и биотехнологии | |
Подразделение | Кафедра медицинской биологии | |
Журнал | Journal of Siberian Federal University. |